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Annals of Medicine

All the Carcinogens We Cannot See

We routinely test for chemicals that cause mutations. What about the dark matter of carcinogens—substances that don’t create cancer cells but rouse them from their slumber?

A New Approach to M.S. Could Transform Treatment of Other Diseases

Multiple sclerosis was once seen as a “dead-end disease.” But lots of little interventions have added up to remarkable progress. Should that change how we take on other conditions?

The Medical Miracle of a Pig’s Heart in a Human Body

The first successful transplantation may solve a donor shortage, but this major scientific advancement is not without challenges.

The Struggle to Define Long COVID

Patients and skeptics are squaring off. Can research heal the rift?

Costa Ricans Live Longer Than We Do. What’s the Secret?

We’ve starved our public-health sector. The Costa Rica model demonstrates what happens when you put it first.

Do Brain Implants Change Your Identity?

As neural devices proliferate, so do reports of personality changes, foundering relationships, and people who want to leave their careers.

When a Virus Is the Cure

As bacteria grow more resistant to antibiotics, bacteriophage therapy is making a comeback.

The Promise and the Peril of Virtual Health Care

During the coronavirus pandemic, telemedicine looks like the future of health care. Is it a future that we want?

Why Weren’t We Ready for the Coronavirus?

The U.S. has fared worse than other countries not because it lacked information or funding but because it failed to learn the lessons of the last outbreaks.

How Anthony Fauci Became America’s Doctor

An infectious-disease expert’s long crusade against some of humanity’s most virulent threats.