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February 2019, Vol 76, No. 2, Pages 105-219

In This Issue of JAMA Psychiatry

Highlights

Abstract Full Text
free access
JAMA Psychiatry. 2019;76(2):105. doi:10.1001/jamapsychiatry.2018.2965
Viewpoint

What Role Should Psychiatrists Have in Responding to the Opioid Epidemic?

Abstract Full Text
JAMA Psychiatry. 2019;76(2):107-108. doi:10.1001/jamapsychiatry.2018.3123

This Viewpoint expresses concerns about the workforce available to care for patients with opioid use disorders and advises that psychiatrists become trained in the administration of buprenorphine and acquire other skills.

Editorial

Use of Prolonged Exposure and Sertraline in the Treatment of Posttraumatic Stress Disorder for Veterans

Abstract Full Text
JAMA Psychiatry. 2019;76(2):109-110. doi:10.1001/jamapsychiatry.2018.3410

Antipsychotics, Excess Deaths, and Paradoxes of Child Psychiatry

Abstract Full Text
JAMA Psychiatry. 2019;76(2):111-112. doi:10.1001/jamapsychiatry.2018.3409

A Status Update on the Association Between Antidepressants and Fractures: Breaking Up?

Abstract Full Text
JAMA Psychiatry. 2019;76(2):113-114. doi:10.1001/jamapsychiatry.2018.3632

The Meaning of Glutamate and the Quest for Biomarkers in the Transition to Psychosis

Abstract Full Text
JAMA Psychiatry. 2019;76(2):115-116. doi:10.1001/jamapsychiatry.2018.3251
Original Investigation

Efficacy of Prolonged Exposure Therapy, Sertraline Hydrochloride, and Their Combination Among Combat Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):117-126. doi:10.1001/jamapsychiatry.2018.3412

This randomized clinical trial compares the relative efficacy of prolonged exposure therapy plus placebo, prolonged exposure therapy plus sertraline hydrochloride, and sertraline plus enhanced medication management in the treatment of posttraumatic stress disorder among combat veterans.

Anxiety, Depression, and Insomnia Among Adults With Opioid Dependence Treated With Extended-Release Naltrexone vs Buprenorphine-Naloxone: A Randomized Clinical Trial and Follow-up Study

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):127-134. doi:10.1001/jamapsychiatry.2018.3537

This randomized clinical trial and open-label follow-up study investigates whether treatment with extended-release naltrexone vs daily treatment with combined buprenorphine-naloxone unmasks or reinforces comorbid symptoms of anxiety, depression, or insomnia in 159 abstinence-motivated adults with opioid dependence.

Patterns of Nonsocial and Social Cognitive Functioning in Adults With Autism Spectrum Disorder: A Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):135-151. doi:10.1001/jamapsychiatry.2018.3645

This systematic review and meta-analysis provides an overview of nonsocial and social cognitive functioning in various domains in adults with autism spectrum disorder, allowing for comparison of the severity of deficits between different domains.

Trends in Serious Psychological Distress and Outpatient Mental Health Care of US Adults

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):152-161. doi:10.1001/jamapsychiatry.2018.3550

This survey study characterizes US national trends in serious psychological distress and trends in outpatient mental health service use by adults with and without serious psychological distress.

Association of Antipsychotic Treatment With Risk of Unexpected Death Among Children and Youths

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):162-171. doi:10.1001/jamapsychiatry.2018.3421

This cohort study of Tennessee Medicaid enrollees from 1999 through 2014 investigates the risk of unexpected death among children and youths aged 5 through 24 years without psychosis who are new users of antipsychotic medications compared with new users of control medications.

Association Between Antidepressant Drug Use and Hip Fracture in Older People Before and After Treatment Initiation

Abstract Full Text
free access
JAMA Psychiatry. 2019;76(2):172-179. doi:10.1001/jamapsychiatry.2018.3679

This population-based study examines the occurrence of hip fractures in elderly individuals before and after initiation of antidepressant medications.

Association of Psychotic Experiences With Subsequent Risk of Suicidal Ideation, Suicide Attempts, and Suicide Deaths: A Systematic Review and Meta-analysis of Longitudinal Population Studies

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):180-189. doi:10.1001/jamapsychiatry.2018.3514

This systematic review and meta-analysis examines longitudinal studies on cohorts of individuals with psychotic experiences to determine their likelihood of suicidal ideation, suicide attempts, and suicide death.

Real-time Mobile Monitoring of the Dynamic Associations Among Motor Activity, Energy, Mood, and Sleep in Adults With Bipolar Disorder

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):190-198. doi:10.1001/jamapsychiatry.2018.3546

This case-control study examines the real-time changes and associations between physical activity, sleep patterns, and energy and mood levels in people with and those without bipolar or depressive disorder.

Association of Hippocampal Glutamate Levels With Adverse Outcomes in Individuals at Clinical High Risk for Psychosis

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):199-207. doi:10.1001/jamapsychiatry.2018.3252

This cross-sectional study investigates whether increased hippocampal glutamate levels are associated with adverse clinical outcomes in individuals at clinical high risk for psychosis compared with healthy control individuals, between clinical high-risk individuals who develop and do not develop psychosis, and between individuals with good and poor outcomes.

Review

Prevention and Treatment of Opioid Misuse and Addiction: A Review

Abstract Full Text
JAMA Psychiatry. 2019;76(2):208-216. doi:10.1001/jamapsychiatry.2018.3126

This narrative review addresses the rewarding and analgesic effects of opioids, the epidemiology of the opioid crisis, and interventions used to treat and prevent opioid use disorder.

Research Letter

Factors Associated With Successful Medication Discontinuation After a Randomized Clinical Trial of Relapse Prevention in First-Episode Psychosis: A 10-Year Follow-up

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):217-219. doi:10.1001/jamapsychiatry.2018.3120

This follow-up study of a randomized clinical trial examines a cohort of patients who had participated in the trial 10 years ago to establish what factors were associated with successful discontinuation of antipsychotic medication regimens.

Correction

Error in Results Sections

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):219. doi:10.1001/jamapsychiatry.2019.0067
JAMA Psychiatry Masthead

JAMA Psychiatry

Abstract Full Text
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JAMA Psychiatry. 2019;76(2):106. doi:10.1001/jamapsychiatry.2018.2966
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