Esben Agerbo, DrMedSc; Patrick F. Sullivan, FRANZCP; Bjarni J. Vilhjálmsson, PhD; et al.
free access
JAMA Psychiatry. 2015;72(7):635-641. doi:10.1001/jamapsychiatry.2015.0346
This case-control study reports that schizophrenia is associated with the polygenic risk score, family psychiatric history, and socioeconomic status.
Genetics of Personality Consortium
free access
has audio
JAMA Psychiatry. 2015;72(7):642-650. doi:10.1001/jamapsychiatry.2015.0554
This genome-wide association analysis identifies a novel locus for neuroticism and shows polygenic association with major depressive disorder (MDD).
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Audio Author Interview:
Neuroticism and Polygenic Association With Major Depressive Disorder (JAMA Psychiatry)
Jean-Baptiste Pingault, PhD; Essi Viding, PhD; Cédric Galéra, MD, PhD; et al.
free access
JAMA Psychiatry. 2015;72(7):651-658. doi:10.1001/jamapsychiatry.2015.0469
This prospective study examines the effects of genes and environment on the developmental course of attention-deficit/hyperactivity disorder (ADHD) symptoms from childhood to adolescence.
Erik Andersson, PhD; Erik Hedman, PhD; Jesper Enander, MSc; et al.
free access
JAMA Psychiatry. 2015;72(7):659-667. doi:10.1001/jamapsychiatry.2015.0546
This randomized clinical trial examines whether d-cycloserine augments cognitive behavioral therapy in the treatment of obsessive-compulsive disorder (OCD) and whether concomitant use of antidepressants moderates the effects of d-cycloserine.
Erik O’Hanlon, PhD; Alexander Leemans, PhD; Ian Kelleher, MD, PhD; et al.
free access
JAMA Psychiatry. 2015;72(7):668-677. doi:10.1001/jamapsychiatry.2015.0137
This population-based, case-control study investigates white matter differences using diffusion-weighted imaging (whole-brain tractography) in adolescents who report psychotic experiences.
Huaiqiang Sun, PhD; Su Lui, MD, PhD; Li Yao, MS; et al.
free access
JAMA Psychiatry. 2015;72(7):678-686. doi:10.1001/jamapsychiatry.2015.0505
This cross-sectional diffusion tensor imaging study found 2 distinct patterns of white matter abnormalities exist at the early phase of schizophrenia, with those having global abnormalities experiencing more severe negative symptoms.
Maria M. Rive, MD; Roel J. T. Mocking, MSc; Maarten W. J. Koeter, PhD; et al.
free access
JAMA Psychiatry. 2015;72(7):687-696. doi:10.1001/jamapsychiatry.2015.0161
This cross-sectional study reports that medication-free patients with major depressive disorder vs bipolar disorder appear to differ in brain activations during emotion regulation, both while depressed and in remission.
John J. McGrath, PhD, MD; Sukanta Saha, PhD; Ali Al-Hamzawi, MD; et al.
free access
JAMA Psychiatry. 2015;72(7):697-705. doi:10.1001/jamapsychiatry.2015.0575
This population epidemiology study uses WHO survey data to provide a comprehensive description of psychotic experiences among adults and serves as a foundation for further research about these rare variegated episodes.
Craig Rodriguez-Seijas, BSc; Malki Stohl, MS; Deborah S. Hasin, PhD; et al.
free access
JAMA Psychiatry. 2015;72(7):706-713. doi:10.1001/jamapsychiatry.2015.0148
To examine the direct and indirect relationships between perceived racial discrimination and common forms of psychopathology, 12 common diagnoses were assessed in a nationally representative sample of African American and Afro-Caribbean adults.
Peter J. Schmidt, MD; Rivka Ben Dor, MD; Pedro E. Martinez, MD; et al.
free access
JAMA Psychiatry. 2015;72(7):714-726. doi:10.1001/jamapsychiatry.2015.0111
This randomized clinical trial notes recurrence of depressive symptoms in perimenopausal women during estradiol withdrawal. See also the editorial by Newhouse and Albert.