Whole grain intake is associated with lower body mass and greater insulin sensitivity among adolescents
- PMID: 12882946
- DOI: 10.1093/aje/kwg146
Whole grain intake is associated with lower body mass and greater insulin sensitivity among adolescents
Abstract
The authors tested the hypothesis that consumption of whole grain is associated with greater insulin sensitivity and lower body mass index (BMI) (weight (kg)/height (m)(2)) in adolescents and that this association is stronger among the heaviest adolescents. Two 127-item food frequency questionnaires were administered at the mean ages of 13 years (standard deviation 1.2) and 15 years (standard deviation 1.3) to 285 Minnesota adolescents who underwent two euglycemic insulin clamp studies 2 years apart as part of a protocol evaluating the influence of insulin resistance on development of adverse cardiovascular disease risk factors. Intake of whole grain was examined for associations with BMI and insulin sensitivity (measured as milligrams of glucose uptake per kilogram of lean body mass (M(lbm)) per minute). After adjustment for age, gender, race, Tanner stage, and energy intake, mean BMI was 23.6 for adolescents consuming less than serving/day of whole-grain foods, 22.6 for -1 servings/day, and 21.9 for more than 1 servings/day (p = 0.05). After adjustment for age, gender, race, Tanner stage, energy intake, BMI, and physical activity, M(lbm) was 11.6, 12.3, and 13.2 mg/kg/minute, respectively, in the three whole grain intake groups (p = 0.02). This relation was stronger among adolescents with higher BMIs (p = 0.001). Whole grain intake was associated with greater insulin sensitivity and lower BMI in adolescents, especially among the heaviest persons.
Similar articles
-
Relationship between whole-grain intake, chronic disease risk indicators, and weight status among adolescents in the National Health and Nutrition Examination Survey, 1999-2004.J Acad Nutr Diet. 2012 Jan;112(1):46-55. doi: 10.1016/j.jada.2011.08.028. Epub 2011 Nov 4. J Acad Nutr Diet. 2012. PMID: 22717176
-
Relationship between whole grain and fiber consumption and body weight measures among 6- to 18-year-olds.J Pediatr. 2010 Oct;157(4):578-83. doi: 10.1016/j.jpeds.2010.04.041. Epub 2010 Jun 12. J Pediatr. 2010. PMID: 20542284
-
Whole grain intake and insulin sensitivity: evidence from observational studies.Nutr Rev. 2004 Jul;62(7 Pt 1):286-91. doi: 10.1111/j.1753-4887.2004.tb00054.x. Nutr Rev. 2004. PMID: 15384920 Review.
-
Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study.Am J Clin Nutr. 2003 Nov;78(5):965-71. doi: 10.1093/ajcn/78.5.965. Am J Clin Nutr. 2003. PMID: 14594783
-
Mechanisms of the effects of grains on insulin and glucose responses.J Am Coll Nutr. 2000 Jun;19(3 Suppl):320S-325S. doi: 10.1080/07315724.2000.10718967. J Am Coll Nutr. 2000. PMID: 10875604 Review.
Cited by
-
Associations between whole grains intake and new-onset hypertension: a prospective cohort study.Eur J Nutr. 2024 May 30. doi: 10.1007/s00394-024-03434-7. Online ahead of print. Eur J Nutr. 2024. PMID: 38814365
-
Metabolic, behavioral health, and disordered eating comorbidities associated with obesity in pediatric patients: An Obesity Medical Association (OMA) Clinical Practice Statement 2022.Obes Pillars. 2022 Aug 6;3:100031. doi: 10.1016/j.obpill.2022.100031. eCollection 2022 Sep. Obes Pillars. 2022. PMID: 37990723 Free PMC article.
-
Evaluation of health and economic effects of United States school meal standards consistent with the 2020-2025 dietary guidelines for Americans.Am J Clin Nutr. 2023 Sep;118(3):605-613. doi: 10.1016/j.ajcnut.2023.05.031. Epub 2023 Jul 30. Am J Clin Nutr. 2023. PMID: 37527964 Free PMC article.
-
The possible relationship between the healthy eating index-2015 and the 10-year risk of cardiovascular diseases.BMC Nutr. 2023 Jun 28;9(1):76. doi: 10.1186/s40795-023-00735-8. BMC Nutr. 2023. PMID: 37370157 Free PMC article.
-
Associations between food groups and liver cancer: a systematic review and meta-analysis of observational studies.Nutr J. 2023 Jun 22;22(1):30. doi: 10.1186/s12937-023-00858-5. Nutr J. 2023. PMID: 37349735 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical