Schizophrenia - MeSH

Select item 680125591.

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Select item 680199672.

Schizophrenia Spectrum and Other Psychotic Disorders

Marked disorders of thought (delusions, hallucinations, or other thought disorder accompanied by disordered affect or behavior), and deterioration from a previous level of functioning. Individuals have one o more of the following symptoms: delusions, hallucinations, and disorganized speech. (from DSM-5)

Year introduced: 2015(1998)

Select item 680125633.

Schizophrenia, Paranoid

A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination.

Year introduced: 1973

Select item 680125624.

Schizophrenia, Disorganized

A type of schizophrenia characterized by frequent incoherence; marked loosening of associations, or grossly disorganized behavior and flat or grossly inappropriate affect that does not meet the criteria for the catatonic type; associated features include extreme social withdrawal, grimacing, mannerisms, mirror gazing, inappropriate giggling, and other odd behavior. (Dorland, 27th ed)

Year introduced: 1981

Select item 680125615.

Schizophrenia, Childhood

An obsolete concept, historically used for childhood mental disorders thought to be a form of schizophrenia. It was in earlier versions of DSM but is now included within the broad concept of PERVASIVE DEVELOPMENT DISORDERS.

Select item 680125606.

Schizophrenia, Catatonic

A type of schizophrenia characterized by abnormality of motor behavior which may involve particular forms of stupor, rigidity, excitement or inappropriate posture.

Year introduced: 1975

Select item 21012177.

Schizophrenia, Treatment-Resistant

A subset of schizophrenia with an inadequate response in target symptoms following treatment with two or more ANTIPSYCHOTICS.

Year introduced: 2022

Select item 680125698.

Schizotypal Personality Disorder

A personality disorder in which there are oddities of thought (magical thinking, paranoid ideation, suspiciousness), perception (illusions, depersonalization), speech (digressive, vague, overelaborate), and behavior (inappropriate affect in social interactions, frequently social isolation) that are not severe enough to characterize schizophrenia.

Year introduced: 1981

Select item 674487229.

DISC2 gene product, human [Supplementary Concept]

RefSeq NR_002227

Date introduced: March 6, 2002

Select item 6741247610.

DISC1 protein, human [Supplementary Concept]

DISC - disrupted in schizophrenia; may have some role in mental illness; RefSeq NM_018662

Date introduced: August 25, 2000

Select item 6753872811.

DISC1 protein, zebrafish [Supplementary Concept]

required for specification of oligodendrocytes and neurons; GenBank EU273350