MeSH

The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired.

Year introduced: 1967(1964)

Adult lactose intolerance due to reduced lactase activity. It is associated with a variation of the MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6 (MCM6) gene. OMIM: 223100

Date introduced: November 5, 2012