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1.

Organometallic Compounds

A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant and Hackh's Chemical Dictionary, 5th ed)

Year introduced: 1968

2.

Trialkyltin Compounds

Organometallic compounds which contain tin and three alkyl groups.

Year introduced: 1975

3.

Metallocenes

Organometallic compounds that generally consist of two cylcopentadiene ANIONS joined in their centers by a metallic cation such as NICKEL; IRON; or TITANIUM.

Year introduced: 2018

4.

Coordination Complexes

Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.

Year introduced: 2010

5.

Gadolinium DTPA

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)

Year introduced: 1998

6.

Technetium Tc 99m Disofenin

A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)

Year introduced: 1998

7.

Technetium Tc 99m Diethyl-iminodiacetic Acid

A nontoxic radiopharmaceutical that is used in the clinical evaluation of hepatobiliary disorders in humans.

Year introduced: 1998

8.

Technetium Tc 99m Dimercaptosuccinic Acid

A nontoxic radiopharmaceutical that is used in the diagnostic imaging of the renal cortex.

Year introduced: 1998

9.

Technetium Tc 99m Lidofenin

A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.

Year introduced: 1998

10.

Technetium Tc 99m Exametazime

A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES.

Year introduced: 1998

11.

Technetium Tc 99m Mertiatide

A technetium diagnostic aid used in renal function determination.

Year introduced: 1993

12.

Technetium Tc 99m Sestamibi

A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.

Year introduced: 1993

13.

Technetium Tc 99m Pentetate

A technetium imaging agent used in renal scintigraphy, computed tomography, lung ventilation imaging, gastrointestinal scintigraphy, and many other procedures which employ radionuclide imaging agents.

Year introduced: 1991

14.

Organotechnetium Compounds

Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.

Year introduced: 1990

15.

Trimethyltin Compounds

Organic compounds composed of tin and three methyl groups. Affect mitochondrial metabolism and inhibit oxidative phosphorylation by acting directly on the energy conserving processes.

Year introduced: 1991(1975)

16.

Triethyltin Compounds

Organic compounds composed of tin and three ethyl groups. Affect mitochondrial metabolism and inhibit oxidative phosphorylation by acting directly on the energy conserving processes.

Year introduced: 1991(1975)

17.

Tetraethyl Lead

A highly toxic compound used as a gasoline additive. It causes acute toxic psychosis or chronic poisoning if inhaled or absorbed through the skin.

Year introduced: 1991(1976)

18.

Phenylmercury Compounds

Organic mercury compounds in which the mercury is attached to a phenyl group. Often used as fungicides and seed treatment agents.

Year introduced: 1980

19.

Phenylmercuric Acetate

A phenyl mercury compound used mainly as a fungicide. Has also been used as a herbicide, slimicide, and bacteriocide.

Year introduced: 1991(1977)

20.

Organotin Compounds

Organic compounds which contain tin in the molecule. Used widely in industry and agriculture.

Year introduced: 1975

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