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1.

Disaccharides

Oligosaccharides containing two monosaccharide units linked by a glycosidic bond.

2.

Chondroitin ABC Lyase

An enzyme that catalyzes the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. (Enzyme Nomenclature, 1992)

Year introduced: 1998

3.

Oligosaccharides

Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.

4.

Muramic Acids

Compounds consisting of glucosamine and lactate joined by an ether linkage. They occur naturally as N-acetyl derivatives in peptidoglycan, the characteristic polysaccharide composing bacterial cell walls. (From Dorland, 28th ed)

Year introduced: 1991(1975)

5.

Melibiose

A disaccharide consisting of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.

Year introduced: 1991(1979)

6.

Isomaltose

A disaccharide consisting of two glucose units in an alpha (1-6) glycosidic linkage.

Year introduced: 1991(1979)

7.

Disaccharidases

Enzymes belonging to the class of GLYCOSIDE HYDROLASES which break down DISACCHARIDES into simpler sugars, MONOSACCHARIDES.

Year introduced: 1974

8.

Cellobiose

A disaccharide consisting of two glucose units in beta (1-4) glycosidic linkage. Obtained from the partial hydrolysis of cellulose.

Year introduced: 1991(1979)

9.

sucromalt [Supplementary Concept]

sweetener produced via enzymatic conversion of sucrose and maltose to a mixture of fructose, leucrose (Disaccharides) and gluco-oligosaccharides

Date introduced: November 29, 2007

10.

QSulf1 [Supplementary Concept]

an extracellular sulfatase which is a candidate developmental regulator of heparan sulfate proteoglycan sulfation in embryonic progenitor lineages. It has an enzymatic domain which functions in the lysosomal degradation of heparan sulfate. It is a heparan sulfate-specific 6-0 endosulfatase with a high degree of substrate specificity for 6-O-sulfated disaccharides of HS chains of HSPG.

Date introduced: September 16, 2003

11.

Glucidex IT 38 [Supplementary Concept]

a mixture of 15% dried aglucose syrup, 13% disaccharides and 72% higher polysaccharides; MW about 600 Da; from maize starch

Date introduced: May 9, 2001

12.

phenyl 1-selenogalactofuranoside [Supplementary Concept]

a glycosyl donor for the synthesis of galactofuranosyl-containing disaccharides

Date introduced: June 1, 1998

13.

gentiobiose [Supplementary Concept]

disaccharide consisting of two glucose units in a beta (1-6) glycosidic linkage; minor descriptor (79-83); on-line & Index Medicus search DISACCHARIDES (79-83); RN given refers to (D)-isomer; structure

Date introduced: August 4, 1983

14.

MsiK protein, Streptomyces [Supplementary Concept]

involved in active transport of mono- and disaccharides in Streptomyces lividans; GenBank U12007

Date introduced: December 30, 1995

15.

ORG 10849 [Supplementary Concept]

the high-affinity heparan sulfate fraction of orgaran (ORG 10172); has high affinity for antithrombin; has a high content of tri- and di-sulfated disaccharides; associated with antithrombin III

Date introduced: December 2, 1994

16.

heparatinase II [Supplementary Concept]

produces disulfated, N-sulfated and N-acetylated, 6-sulfated disaccharides from heparan sulfate

Date introduced: November 24, 1993

17.

heparatinase I [Supplementary Concept]

produces N-acetylated or N-sulfated disaccharides from heparan sulfate, breaking glucosaminido-glucuronic acid linkages; does not act if there is a 6-sulfate group on the glucosamine moiety

Date introduced: November 24, 1993

18.

saccharide kinase [Supplementary Concept]

found in Helicobacter pylori; incubation with ATP and mono- or disaccharides only gave glucose 6-phosphate; other saccharides were not phosphorylated

Date introduced: February 20, 1993

19.

UDP-acetylglucosamine-beta-D-galactosylsaccharide acetylglucosaminyltransferase [Supplementary Concept]

transfers 2-acetamido-2-deoxy-D-glucose from UDP-2-acetamido-2-deoxy-D-glucose to terminal nonreducing beta-D-galactosyl residues in disaccharides, oligosaccharides, glycoproteins & glycolipids; detected in human serum

Date introduced: November 21, 1983

20.

lactosaminoglycan [Supplementary Concept]

cell surface glycoconjugate of embryonal carcinoma cells; core structure composed of repeating N-acetyllactosamine (Gal-GlcNAc) disaccharides; branched lactosaminoglycan from Band 3 gloycoprotein of adult human erythrocytes

Date introduced: November 14, 1983

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