"Autoantibodies" - MeSH

Autoantibodies against contactin-associated protein-like 2 (CASPR2). Presence of anti-CASPR2 auto antibodies is associated with CORTICAL DYSPLASIA-FOCAL EPILEPSY SYNDROME.

Date introduced: August 20, 2021

Select item 680192686.

Antibodies, Antineutrophil Cytoplasmic

Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.

Year introduced: 1997

Select item 680188287.

Immunoglobulins, Thyroid-Stimulating

Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.

Year introduced: 1995

Select item 20234438.

Anti-Citrullinated Protein Antibodies

Autoantibodies to citrullinated-peptides and proteins.

Year introduced: 2018

Select item 680171529.

Antibodies, Antiphospholipid

Autoantibodies directed against phospholipids. These antibodies are characteristically found in patients with certain autoimmune diseases (e.g., SYSTEMIC LUPUS ERYTHEMATOSUS and ANTIPHOSPHOLIPID SYNDROME), some non-autoimmune diseases, and also in healthy individuals.

Year introduced: 1993

Select item 210065110.

anti-thyroid autoantibodies [Supplementary Concept]

Date introduced: September 3, 2021

Select item 210063711.

anti-scl-70 autoantibodies [Supplementary Concept]

Date introduced: September 2, 2021

Select item 210063012.

anti-RNA-polymerase III autoantibody [Supplementary Concept]

Date introduced: September 2, 2021

Select item 6801715313.

Antibodies, Anticardiolipin

Antiphospholipid antibodies found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. The antibodies are detected by solid-phase IMMUNOASSAY employing the purified phospholipid antigen CARDIOLIPIN.

Year introduced: 1993

Select item 6801555114.

Autoimmunity

Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES.

Year introduced: 1990

Select item 210147615.

anti-citrullinated filaggrin autoantibodies [Supplementary Concept]

Date introduced: November 29, 2021

Select item 210077916.

anti-transglutaminase autoantibody [Supplementary Concept]

Date introduced: September 23, 2021

Select item 210064917.