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DNA Cleavage

A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.

Year introduced: 2007

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Subheadings:

    Tree Number(s): G02.111.210, G05.193

    MeSH Unique ID: D053837

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