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Review
. 2020 May 27;25(11):2491.
doi: 10.3390/molecules25112491.

Supercritical Fluid Applications in the Design of Novel Antimicrobial Materials

Irena Zizovic  1
Affiliations
Review

Supercritical Fluid Applications in the Design of Novel Antimicrobial Materials

Irena Zizovic. Molecules. .

Abstract

Bacterial resistance to antibiotics is one of the biggest problems in the modern world. The prevention of bacterial spreading from hospitals to the community and vice versa is an issue we have to deal with. This review presents a vast potential of contemporary high-pressure techniques in the design of materials with antimicrobial activity. Scientists from all over the world came up with ideas on how to exploit extraordinary properties of supercritical fluids in the production of advantageous materials in an environmentally friendly way. The review summarizes reported methods and results.

Keywords: antibacterial activity; antibacterial materials; bacterial resistance; carbon dioxide; green chemistry; material design; multidrug resistance; supercritical fluid.

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Simplified presentation of Supercritical Solvent Impregnation (SSI) modes: (a) batch; (b) semi-continuous.
Figure 2
Figure 2
Integrated supercritical fluid extraction - impregnation (SFE-SSI) process.
Figure 3
Figure 3
SEM images of the neat cellulose acetate-based polymer (a), and the cellulose acetate-based polymer loaded with thymol (b), after the exposure to S. aureus [56].
Figure 4
Figure 4
Simplified presentation of Supercritical Assisted Impregnation (SAI)/High-Pressure Assisted Impregnation (HPAI) process.
See this image and copyright information in PMC

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