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Comparative Study
. 1991;41(3):255-7.
doi: 10.1007/BF00315439.

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

T Tsuchihashi  1 , A Tsukashima, K Matsumura, I Abe, M Tominaga, Y Nakao, K Kobayashi, M Fujishima
Affiliations
Comparative Study

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

T Tsuchihashi et al. Eur J Clin Pharmacol. 1991.

Abstract

A newly developed calcium antagonist, nilvadipine, was administered to 7 hypertensive patients aged 75.6 y. Nilvadipine 4 mg b.d. decreased the average 24-h blood pressure significantly from 169/89 mmHg to 152/81 mmHg after 7 to 14 days without any change in the pulse rate. The circadian patterns of blood pressure and pulse rate were not affected by nilvadipine. Although the present study was a preliminary one done over a short period in a small number of patients, the results suggest that nilvadipine exerts an antihypertensive effect without altering the circadian pattern or the variability of blood pressure in elderly hypertensive patients.

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