Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies
- PMID: 16247045
- DOI: 10.1212/01.wnl.0000180600.09719.53
Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies
Abstract
Background: Fruit and vegetable consumption is associated with lower rates of coronary heart disease. Results from observational studies suggest a similar association with stroke.
Objective: To assess the evidence from prospective observational studies on fruit and vegetable intake and risk of stroke.
Methods: A meta-analysis of prospective studies was conducted to examine the association between fruit and vegetable intake and stroke. Studies were selected if they reported relative risk (RR) and 95% CI for any type of stroke and used a validated questionnaire for food intake assessment. Pooled RR were calculated and linearity of the associations was examined.
Results: Seven studies were eligible for the meta-analysis, including 90,513 men, 141,536 women, and 2,955 strokes. The risk of stroke was decreased by 11% (RR 95% CI: 0.89 [0.85 to 0.93]) for each additional portion per day of fruit, by 5% (RR: 0.95 [0.92 to 0.97]) for fruit and vegetables, and by 3% (RR: 0.97 [0.92 to 1.02]; NS) for vegetables. The association between fruit or fruit and vegetables and stroke was linear, suggesting a dose-response relationship.
Conclusions: This meta-analysis of cohort studies suggests that fruit and fruit and vegetable consumption decreases the risk of stroke.
Summary for patients in
-
Patient page. Fruit and the brain: the more the better!Neurology. 2005 Oct 25;65(8):E17-8. doi: 10.1212/01.wnl.0000185440.55813.27. Neurology. 2005. PMID: 16247035 No abstract available.
Similar articles
-
Fruit and vegetable consumption and risk of depression: accumulative evidence from an updated systematic review and meta-analysis of epidemiological studies.Br J Nutr. 2018 May;119(10):1087-1101. doi: 10.1017/S0007114518000697. Br J Nutr. 2018. PMID: 29759102
-
Monounsaturated Fatty Acid Intake and Stroke Risk: A Meta-analysis of Prospective Cohort Studies.J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1326-34. doi: 10.1016/j.jstrokecerebrovasdis.2016.02.017. Epub 2016 Mar 14. J Stroke Cerebrovasc Dis. 2016. PMID: 26987490 Review.
-
Raw and processed fruit and vegetable consumption and 10-year stroke incidence in a population-based cohort study in the Netherlands.Eur J Clin Nutr. 2011 Jul;65(7):791-9. doi: 10.1038/ejcn.2011.36. Epub 2011 Mar 23. Eur J Clin Nutr. 2011. PMID: 21427746
-
Fruit and vegetable consumption and stroke: meta-analysis of cohort studies.Lancet. 2006 Jan 28;367(9507):320-6. doi: 10.1016/S0140-6736(06)68069-0. Lancet. 2006. PMID: 16443039 Review.
-
Fruit and vegetable intake in relation to risk of ischemic stroke.JAMA. 1999 Oct 6;282(13):1233-9. doi: 10.1001/jama.282.13.1233. JAMA. 1999. PMID: 10517425
Cited by
-
A Review of Healthy Dietary Choices for Cardiovascular Disease: From Individual Nutrients and Foods to Dietary Patterns.Nutrients. 2023 Nov 23;15(23):4898. doi: 10.3390/nu15234898. Nutrients. 2023. PMID: 38068756 Free PMC article. Review.
-
Association of Vegetable Consumption with Stroke in China: A Longitudinal Study.Nutrients. 2023 Mar 24;15(7):1583. doi: 10.3390/nu15071583. Nutrients. 2023. PMID: 37049422 Free PMC article.
-
The Chemical Variability, Nutraceutical Value, and Food-Industry and Cosmetic Applications of Citrus Plants: A Critical Review.Antioxidants (Basel). 2023 Feb 14;12(2):481. doi: 10.3390/antiox12020481. Antioxidants (Basel). 2023. PMID: 36830039 Free PMC article. Review.
-
Raman Spectroscopy of Carotenoid Compounds for Clinical Applications-A Review.Molecules. 2022 Dec 17;27(24):9017. doi: 10.3390/molecules27249017. Molecules. 2022. PMID: 36558154 Free PMC article. Review.
-
Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies.BMC Med. 2022 May 24;20(1):194. doi: 10.1186/s12916-022-02381-6. BMC Med. 2022. PMID: 35606791 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
