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Biomarkers In Prediction of Acute Mesenteric Ischaemia: a prospective multicentre study (BIPAMI study): a study protocol
BackgroundAcute mesenteric ischaemia (AMI) is a life-threatening disease where early diagnosis is critical to avoid morbidity and mortality from...
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Treatment Strategies for Filamentous Fungi Keratitis
IntroductionThis research aims to describe clinical findings, epidemiology and treatment outcomes in patients with filamentous fungi keratitis of a...
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Insomnia During Late Life: Potential Pathways Toward Suicide Risk
Purpose of ReviewAs the global population continues to age, the identification of drivers of suicide risk in older adults is of increasing...
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Semaphorin 3C (Sema3C) reshapes stromal microenvironment to promote hepatocellular carcinoma progression
More than 90% of hepatocellular carcinoma (HCC) cases develop in the presence of fibrosis or cirrhosis, making the tumor microenvironment (TME) of...
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Prolonged water-only fasting in the management of low-grade follicular lymphoma: a case series
BackgroundFollicular lymphoma typically follows an indolent and relapsing course often requiring several treatment cycles to achieve remission. Some...
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In silico exploration of anti-prostate cancer compounds from differential expressed genes
Prostate cancer (PCa) is a complex and biologically diverse disease with no curative treatment options at present. This study aims to utilize...
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Drug-related emergency department visits: external validation of an assessment tool in a general emergency department population
BackgroundThe process of identifying drug-related hospitalisations is subjective and time-consuming. Assessment tool for identifying hospital...
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A Novel Combination Strategy of Ultrasound-Guided Percutaneous Radiofrequency Ablation and Corticosteroid Injection for Treating Recalcitrant Plantar Fasciitis: A Retrospective Comparison Study
IntroductionThe best treatment yielding clinical benefits was still equivocal and controversial for the treatment of recalcitrant plantar fasciitis...
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Preparation, optimization, and characterization of genistein-ginseng long-acting polymeric gel as a breast cancer treatment alternative
To address the prevalent genistein (GST) metabolism and inadequate intestinal absorption, an oral long-acting and gastric in-situ gelling gel was...
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Platr3/NUDT21/NF-κB Axis Mediates P. gingivalis-Suppressed Cementoblast Mineralization
Porphyromonas gingivalis ( P. gingivalis ) is one of the major pathogens causing periodontitis and apical periodontitis (AP). Long noncoding RNA...
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Alternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
ObjectiveThe purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate...
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Conservative Management of Occipital Neuralgia Supported by Physical Therapy: A Review of Available Research and Mechanistic Rationale to Guide Treatment
Purpose of ReviewConservative management is consistently recommended as a first line intervention for occipital neuralgia (ON); however, there is...
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The efficacy and safety of combined therapy with endobronchial tamponade and bronchial artery embolization for massive hemoptysis
BackgroundMassive hemoptysis is characterized by its life-threatening nature, potentially leading to airway obstruction and asphyxia. The objective...
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Gender Differences in Perceptions of Psoriatic Arthritis Disease Impact, Management, and Physician Interactions: Results from a Global Patient Survey
IntroductionWe evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and...
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Timely initiation of complementary feeding and associated factors among mothers having children aged 6 to 24 months in North-West Ethiopia: a comparative cross-sectional study
BackgroundThe timely introduction of complementary foods during infancy is necessary for nutritional reasons, and to enable the transition from milk...
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Radiopalmar ganglion cysts: prevalence, morphology, and clinical significance in wrist MRI
ObjectivesTo assess radiopalmar ganglion cysts’ (RPG) prevalence, morphology, and clinical significance in consecutive patients.
Materials and methods ... -
The metabolic consequences of ‘yo-yo’ dieting are markedly influenced by genetic diversity
BackgroundWeight loss can improve the metabolic complications of obesity. However, it is unclear whether insulin resistance persists despite weight...
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Small molecule tyrosine kinase inhibitors approved for systemic therapy of advanced hepatocellular carcinoma: recent advances and future perspectives
Liver cancer is the sixth most commonly diagnosed cancer and the third leading cause of cancer death in the world, and hepatocellular carcinoma (HCC)...
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Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
The preferential response to PARP inhibitors (PARPis) in BRCA-deficient and Schlafen 11 (SLFN11)-expressing ovarian cancers has been documented, yet...
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The Urban–Rural Divide in Neurocritical Care in Low-Income and Middle-Income Countries
The term “urban–rural divide” encompasses several dimensions and has remained an important concern for any country. The economic disparity; lack of...