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Data-driven meal events detection using blood glucose response patterns
BackgroundIn the Diabetes domain, events such as meals and exercises play an important role in the disease management. For that, many studies focus...
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Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers
IntroductionGlucokinase (GK) plays a pivotal role in maintaining glucose homeostasis; globalagliatin, a newly developed drug, is a GK activator...
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Effectiveness of personalized meal recommendation in improving dietary behaviors of Chinese community-dwelling elders: study protocol for a cluster randomized controlled trial
BackgroundInappropriate eating behaviors, particularly a lack of food diversity and poor diet quality, have a significant impact on the prognosis of...
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A low-calorie meal replacement improves body composition and metabolic parameters in shift workers with overweight and obesity: a randomized, controlled, parallel group trial
BackgroundShift work has been identified as a risk factor for several chronic health conditions including obesity. This study evaluated the impact of...
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Meal replacement as a weight loss strategy for night shift workers with obesity: a protocol for a randomized controlled trial
BackgroundShift work is considered a risk factor for a number of chronic health conditions including obesity. Weight reduction in obese patients...
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The vascular function effects of adding exenatide or meal insulin to basal insulin therapy in early type 2 diabetes
ObjectiveBasal insulin glargine has a neutral effect on cardiovascular risk in type 2 diabetes (T2DM). In practice, basal insulin is often paired...
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A plant-based meal reduces postprandial oxidative and dicarbonyl stress in men with diabetes or obesity compared with an energy- and macronutrient-matched conventional meal in a randomized crossover study
BackgroundIncreased oxidative/dicarbonyl stress and chronic inflammation are considered key pathophysiological mediators in the progression of...
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After Dinner Rest a While, After Supper Walk a Mile? A Systematic Review with Meta-analysis on the Acute Postprandial Glycemic Response to Exercise Before and After Meal Ingestion in Healthy Subjects and Patients with Impaired Glucose Tolerance
BackgroundThe most effective way to cope with high blood sugar spikes is to engage in physical activity in temporal proximity to food intake....
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Effect of mulberry fruit extract on glucose fluxes after a wheat porridge meal: a dual isotope study in healthy human subjects
BackgroundPrevious research has shown the efficacy of mulberry extracts for lowering post-prandial glucose (PPG) responses. The postulated mechanism...
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Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions
Aims/hypothesisSleep, diet and exercise are fundamental to metabolic homeostasis. In this secondary analysis of a repeated measures, nutritional...
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Estimation of meal portions in bulimia nervosa compared to anorexia nervosa and healthy controls
PurposeBulimia nervosa (BN) and anorexia nervosa (AN) are potentially life-threatening eating disorders (ED) that primarily affect young people,...
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The role of Helicobacter suis, Fusobacterium gastrosuis, and the pars oesophageal microbiota in gastric ulceration in slaughter pigs receiving meal or pelleted feed
This study investigated the role of causative infectious agents in ulceration of the non-glandular part of the porcine stomach ( pars oesophagea ). In...
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The Impact of Pre-Exercise Carbohydrate Meal on the Effects of Yerba Mate Drink on Metabolism, Performance, and Antioxidant Status in Trained Male Cyclists
IntroductionThe consumption of yerba mate (YM), a source of antioxidants, in a fasted state increases fatty acid oxidation (FAT ox ) during...
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Energy intake estimation using a novel wearable sensor and food images in a laboratory (pseudo-free-living) meal setting: quantification and contribution of sources of error
ObjectivesDietary assessment methods not relying on self-report are needed. The Automatic Ingestion Monitor 2 (AIM-2) combines a wearable camera that...
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Pharmacokinetics and Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers: An Open, Randomized, Single-Dose, Three-Period, Three-Sequence Crossover Study
Background and ObjectiveAbiraterone acetate tablet is an inhibitor of androgen synthesis, primarily for the treatment of metastatic...
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Edograms: recording the microstructure of meal intake in humans—a window on appetite mechanisms
Early attempts at the objective measurement of food intake in humans followed many heuristic pioneer studies in laboratory animals, which revealed...
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Acute assessment of subjective appetite and implicated hormones after a hypnosis-induced hallucinated meal: a randomized cross-over pilot trial
The use of hypnosis can generate hallucinatory phenomena, which ranged from vivid/auditory imagery to fully developed “hallucinations” in selected...
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Effect of two insect meals on the gut commensal microbiome of healthy sea trout (Salmo trutta vr. trutta)
BackgroundThe balance of the intestinal commensal microbiome of fish and other animals plays an important role in the physiological processes of...
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Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults
Background and ObjectivesThis study was conducted to investigate the effect of high-fat meals on the pharmacokinetics (PK) and safety profile of...
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Cross-sectional associations of actigraphy-assessed sleep with dietary outcomes in emerging adults
Background/objectivesEmerging adults (~18–28 years of age) have a high prevalence of poor sleeping habits and poor diet quality; however, little is...