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An enduring debate on gliomatosis cerebri
Gliomatosis cerebri (GC) is a unique glial tumor that extensively invades the cerebral white matter and has been recognized as an entity of...
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Revisiting prognostic factors of gliomatosis cerebri in adult-type diffuse gliomas
PurposeThere is lack of comprehensive analysis evaluating the impact of clinical, molecular, imaging, and surgical data on survival of patients with...
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Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
Lymphomatosis cerebri (LC) is a rare type of primary central nervous system lymphoma with diffuse, nonenhancing infiltrative lesions and is often...
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Clinical characteristics and radiological features of glioblastoma, IDH-wildtype, grade 4 with histologically lower-grade gliomas
The 2021 World Health Organization (WHO) classification of central nervous system tumors applied molecular criteria and further integrated...
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Gliomatosis cerebri (GC) or GC-like? A picture to be reconsidered in neuro-oncology based on large retrospective analysis of GC series
IntroductionGliomatosis cerebri (GC), defined until 2016 as a distinct astrocytic glioma entity, has been removed from the 2016 World Health...
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Gliomatosis cerebri: a consensus summary report from the Second International Gliomatosis cerebri Group Meeting, June 22–23, 2017, Bethesda, USA
Gliomatosis cerebri (GC) is an aggressive glioma characterized by an invasive growth pattern and a dismal prognosis. The low incidence and...
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Clinical and imaging characteristics of supratentorial glioma with IDH2 mutation
PurposeThe rarity of IDH2 mutations in supratentorial gliomas has led to gaps in understanding their radiological characteristics, potentially...
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Capturing evolving definitions of 12 select rare CNS tumors: a timely report from CBTRUS and NCI-CONNECT
PurposeIncidence, prevalence, and survival are population-based statistics describing cancer burden. The National Cancer Institute’s (NCI)...
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Heterogeneity of glioblastoma with gliomatosis cerebri growth pattern on diffusion and perfusion MRI
Background and purposeGliomatosis cerebri (GC) is a rare growth pattern of glioblastoma whose diffuse nature is reflected by unspecific, relatively...
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Supratentorielle Hirntumoren im Kindesalter
BackgroundPediatric brain tumors differ regarding location and histopathological features compared to those in adults. In children, 30% of pediatric...
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Clinical, neuroimaging and histopathological features of gliomatosis cerebri: a systematic review based on synthesis of published individual patient data
IntroductionGliomatosis cerebri (GC) is a rare fatal widespread infiltrating CNS tumor. As consistent disease features have not been established, the...
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How I treat recurrent pediatric high-grade glioma (pHGG): a Europe-wide survey study
PurposeAs there is no standard of care treatment for recurrent/progressing pediatric high-grade gliomas (pHGG), we aimed to gain an overview of...
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Lewy body disease as a potential negative outcome modifier of glioblastoma treatment: a case report
BackgroundElderly patients with glioblastoma are particularly susceptible to the adverse effects of ionizing radiation to the brain. This population...
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A phase I trial of lenalidomide and radiotherapy in children with diffuse intrinsic pontine gliomas or high-grade gliomas
PurposeThis study was performed to determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of the immunomodulatory agent,...
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[18F]FET-PET in children and adolescents with central nervous system tumors: does it support difficult clinical decision-making?
PurposePositron emission tomography (PET) with O-(2-[ 18 F]fluoroethyl)-L-tyrosine ([ 18 F]FET) is a well-established tool for non-invasive assessment...
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Incidence and survival of gliomatosis cerebri: a population-based cancer registration study
Gliomatosis cerebri (GC) comprises a rare widespread infiltrating growth pattern of diffuse gliomas. We explored the incidence patterns and survival...
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Progressive leukoencephalopathy as a manifestation of primary angiitis of the central nervous system: case report and review of the literature
Background and objectivePrimary angiitis of the central nervous system (PACNS) is a rare form of vasculitis solely affecting the vessels of the...
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Adult-type and Pediatric-type Diffuse Gliomas
The classification of diffuse gliomas into the adult type and the pediatric type is the new basis for the diagnosis and clinical evaluation. The...
