Explore the latest in adverse drug events, including postmarketing surveillance, risk mitigation, and the pharmacogenetics of safety.
This cohort study investigates associations between gender-affirming hormone treatment and development and progression of metabolic syndrome among transgender veterans compared with cisgender veterans.
This randomized clinical trial assesses whether sensorimotor training and whole-body vibration training reduce symptoms and decrease the onset of chemotherapy-induced peripheral neuropathy.
This qualitative study using a mixed-methods approach examines the identification of and proposed measures to address administrative harms.
This cohort study identifies the most potentially hepatotoxic medications based on clinical incidence rates of hospitalizations for severe acute liver injury (ALI) and examines how these rates compare with the hepatotoxicity categorization of severe ALI using published case reports.
This case report describes dusky red to violaceous lesions with desquamation on the wrists and dorsal surface of both hands and near the Achilles tendon that occurred after intravenous paclitaxel treatment for invasive ductal carcinoma of the breast.
This JAMA Insights examines the adverse effects of homelessness on physical and mental health and suggests strategies to improve access to health care, services, and housing for people experiencing homelessness.
This systematic review and network meta-analysis assesses which total neoadjuvant treatment regimens are associated with the highest pathological complete response rates compared with standard long-course chemoradiotherapy in the treatment of locally advanced rectal cancer.
This cross-sectional study examines the levels of lead in household drinking water of individuals with kidney failure.
This nonrandomized controlled trial assessed the benefits and toxic effects of intensity-modulated reirradiation therapy with nivolumab in the treatment of patients with recurrent or second primary head and neck squamous cell carcinoma.
This cohort study examines patients with drug reaction with eosinophilia and systemic symptoms who also have pustules.
This cohort study investigates demographic and clinical patient characteristics associated with risk of hydroxychloroquine retinopathy.
This phase 1 dose-escalation trial examines whether inotuzumab ozogamicin plus dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (EPOCH) is safe and effective for adults with relapsed or refractory B-cell acute lymphoblastic leukemia or lymphoma (ALL).
This economic evaluation examines the cost-effectiveness of HLA-B*15:02 genotyping in Asian Australian patients with epilepsy.
This case series describes a constellation of novel adverse reactions in 3 of 9 patients with uveal melanoma receiving treatment targeting activity of the Brahma-associated factor chromatin remodeling complex.
This cohort study assesses treatment patterns and attrition rates in patients with advanced urothelial carcinoma in US oncology clinics.
This JAMA Insights discusses the adverse effects of climate change on mental health and proposes solutions to help mitigate those effects.
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